The Challenge
Breaking PCBs out of a panel (known as depaneling) involves snapping or cutting the boards along pre-designed perforated tabs ("mouse bites") or V-scored grooves. This step and the subsequent cleaning imposes some risk of damage to the PCBA that can't be ignored. Therefore it is generally preferred to test PCBAs after depanelization. Individual testing also generally provides better access for side-approach. On the other hand, testing in a panel provides an easy way to (1) test multiple devices in parallel, (2) align the devices, and (3) reduce handling time while doing that.
